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Week 13 of the NFL Fantasy football season is here, and there are some exciting matchups to consider when setting your lineup. With all teams in action and no bye weeks, fantasy managers have a full slate of players to choose from. However, it’s not just about picking individual players; it’s also important to consider the defenses they will be facing.

For example, running backs Bucky Irving and Rachaad White have a favorable matchup against the Panthers defense, which has allowed the most Fantasy points to opposing running backs in 2024. On the other hand, the Vikings defense has been stingy against the run, making James Conner a risky start against them.

To help make informed decisions, SportsLine has released its Week 13 Fantasy football rankings based on a proven computer model that has a track record of success. This model has consistently outperformed human experts in past seasons, giving fantasy managers an edge when setting their lineups.

When it comes to quarterbacks, Joe Burrow of the Cincinnati Bengals tops the rankings for Week 13. Despite his team’s record, Burrow has put up impressive numbers and has a favorable matchup against the Steelers. Other top QB picks include Josh Allen of the Buffalo Bills and Lamar Jackson of the Baltimore Ravens.

In the running back category, Saquon Barkley of the Philadelphia Eagles leads the rankings, followed by Christian McCaffrey of the San Francisco 49ers and Joe Mixon of the Houston Texans. These players have been putting up big numbers and are poised to have a strong Week 13 performance.

For wide receivers, Ja’Marr Chase of the Cincinnati Bengals, Nico Collins of the Houston Texans, and Puka Nacua of the Los Angeles Rams are the top picks. These players have been consistent producers and have favorable matchups in Week 13.

At tight end, Taysom Hill of the New Orleans Saints, George Kittle of the San Francisco 49ers, and Trey McBride of the Arizona Cardinals are the top choices. These players have been reliable targets for their quarterbacks and have the potential for a big game in Week 13.

When it comes to defense/special teams, the Broncos, Jets, and Commanders are the top picks for Week 13. These defenses have favorable matchups and are expected to put up solid numbers.

To get the full Week 13 Fantasy football rankings and make informed decisions for your lineup, head to SportsLine now. The model has identified some surprising picks that could give you an edge in your league. Don’t miss out on the opportunity to make strategic choices and potentially lead your team to victory in Week 13.