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Backing the Detroit Lions has proven to be a successful strategy for NFL betting this season. The Lions have won six games in a row and have a 7-1 record against the spread in 2024. Additionally, Detroit has covered the spread in their last seven road games dating back to last season. This Sunday, the Lions will face the Houston Texans on Sunday Night Football, with Detroit being a 3.5-point favorite according to the latest Week 10 NFL odds. Other notable Week 10 NFL spreads include Steelers vs. Commanders (-2.5, 45), 49ers vs. Buccaneers (+6, 50.5), and Eagles vs. Cowboys (+7, 43.5).

For those seeking NFL picks, NFL parlays, Fantasy football rankings, or NFL DFS picks for Week 10, SportsLine offers a comprehensive guide with its proven model, AI PickBot, and team of experts. The AI PickBot has been successful in making picks, with 1,947 4.5- and 5-star sports betting picks since last season. It is backing the Rams as one-point home favorites against the Dolphins on Monday Night Football. In addition to AI picks, SportsLine’s model has created a five-team parlay for Week 10 that pays 25-1, with Chicago (-6.5, 38.5) being one of the legs.

SportsLine’s model also simulates every game 10,000 times to produce accurate Fantasy rankings. The Week 10 Fantasy football positional rankings are available to help with start-sit decisions. For those looking for Fantasy football waiver wire options, R.J. White from SportsLine breaks down the best widely available players heading into Week 10. These players can make an impact not only this week but also throughout the season.

In terms of NFL DFS picks, SportsLine has a DFS optimizer that uses information from the SportsLine Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks for any slate on sites like FanDuel and DraftKings. The DFS rankings for Week 10 are available, with players like Falcons running back Bijan Robinson and Vikings wide receiver Justin Jefferson highlighted as top picks.

Furthermore, SportsLine’s model, which has had a successful betting streak, offers picks for every game in Week 10. The model’s favorite pick is the Texans (+3.5, 49) to cover at home against the Lions. Additionally, NFL experts like Mike Tierney and Eric Cohen provide insights and best bets for Week 10 games, along with exact score predictions for each matchup.

For the Thursday Night Football game between the Bengals and Ravens, SportsLine’s model likes the Over (52.5) and has picks on the spread and money line. NFL expert Mike Tierney, who has a strong record on Ravens games, has also analyzed this matchup and provided his best bet for TNF.

Overall, SportsLine offers a wealth of resources for NFL betting, Fantasy football, and DFS picks, making it a one-stop destination for all football enthusiasts. From AI picks to expert insights, SportsLine provides valuable information to help fans make informed decisions when it comes to NFL betting and Fantasy football.