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Week 13 of Fantasy football is here, and with no teams on a bye, lineups are looking stacked. It’s essential to consider not only individual players but also the defenses they are facing when making your picks for this week. Running backs like Bucky Irving and Rachaad White, who may usually be flex options, have a chance to shine against a Panthers defense that has struggled against opposing running backs this season.

On the other hand, the Vikings have been tough against the run, making James Conner a player to watch as he faces them in Week 13. Before finalizing your lineup, it’s wise to check out the Week 13 Fantasy football rankings from SportsLine’s proven computer model. The model has a track record of outperforming human experts and can give you an edge in your league.

When it comes to quarterbacks, players like Joe Burrow, Josh Allen, and Lamar Jackson are top picks for Week 13. Burrow has been impressive despite the Bengals’ record, while Allen has been a driving force for the Bills. Jackson, despite a recent tough matchup, remains a strong contender based on his season performance.

In the running back category, Saquon Barkley, Christian McCaffrey, and Joe Mixon are leading the pack. Barkley has been on fire recently, while McCaffrey is a reliable option for the 49ers. Mixon has flourished in his new team, the Texans, and is worth considering for your lineup.

For wide receivers, Ja’Marr Chase, Nico Collins, and Puka Nacua are standouts for Week 13. Chase has been a force to be reckoned with this season, leading in receiving yards and touchdowns. Collins and Nacua have also been putting up impressive numbers and have favorable matchups in Week 13.

In the tight end category, players like Taysom Hill, George Kittle, and Trey McBride are top picks. Hill’s versatility makes him a valuable asset, while Kittle has been consistent for the 49ers. McBride, despite flying under the radar, is a strong choice based on his target share.

When it comes to defense, the Broncos, Jets, and Commanders are top choices for Week 13. These defenses have favorable matchups and can help bolster your Fantasy lineup.

To get the full Week 13 Fantasy football rankings and make informed decisions for your lineup, head to SportsLine now. The model has identified some surprising picks that could give you an edge in your league. Don’t miss out on the opportunity to make winning calls for Week 13.