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The Seattle Seahawks (3-2) are set to take on the San Francisco 49ers (2-3) in a Thursday Night Football matchup to kick off Week 6 of the NFL season. The 49ers are looking to bounce back after a close loss to the Arizona Cardinals last week, while the Seahawks are coming off a defeat at the hands of the New York Giants. Kickoff is scheduled for 8:15 p.m. ET at Lumen Field in Seattle, Wash.

According to the latest odds from SportsLine Consensus, the 49ers are favored by 3.5 points with an over/under of 49 points. The Niners are also -185 money-line favorites, while the Seahawks are the underdogs at +154. Before making any picks, it’s important to consider the insights and predictions from expert Micah Roberts, who has a strong track record with picks involving San Francisco.

Roberts, who has over 20 years of experience in the Las Vegas sportsbook industry, has an impressive 23-5 record on his last 28 picks involving the 49ers. He has now shared his picks and predictions for the Seahawks vs. 49ers game. For more details on his analysis, head to SportsLine.

When it comes to the game itself, the 49ers boast one of the top offensive units in the league. Quarterback Brock Purdy has been impressive, ranking fourth in passing yards and seventh in QBR. Running back Jordan Mason is also a force to be reckoned with, leading the league in carries and ranking second in rushing yards.

On the other side, the Seahawks have a potent offense led by quarterback Geno Smith, who leads the league in passing yards. Receiver DK Metcalf is a key playmaker for Seattle, ranking fourth in receiving yards. The Seahawks will be looking to capitalize on their offensive strengths to secure a win against the 49ers.

Roberts has thoroughly analyzed the matchup and identified a critical X-factor that will impact the outcome of the game. While he is leaning towards the over on the total points, he has also pinpointed a key factor that will heavily influence the spread. To find out which team Roberts is backing and the reasoning behind his pick, visit SportsLine.

With the game set to unfold on Thursday Night Football, fans and bettors alike will be eagerly awaiting the showdown between the 49ers and Seahawks. Be sure to tune in to see whether San Francisco can cover the spread as the favorite, or if Seattle will pull off an upset on their home turf.